Release date: 2010-07-21
Ti2448 new medical titanium alloy developed by Yang Rui and Hao Yulin of Engineering Materials Research Department of Shenyang Materials Science National Research Institute of Metal Research Institute of Chinese Academy of Sciences was recently authorized by the United States. At the same time, two types of implant devices, such as orthopedic bone plate and spinal fixation system made of Ti2448 alloy, have completed clinical trials in several hospitals and entered the stage of scale application.
Ti2448 titanium alloy is the lowest titanium alloy with the lowest Young's modulus to date. It has excellent biocompatibility and mechanical compatibility with human tissue, and is a new biomedical metal material with human bone bionic characteristics. The alloy has excellent properties such as high strength, high damping, superelasticity, and easy processing and easy welding. It also has important potential applications in advanced engineering such as aerospace. The excellent properties of Ti2448 alloy are partly due to the unique deformation mechanism. In the past, the superelasticity of metallic materials mostly originated from stress-induced reversible martensitic transformation. In addition to the martensite transformation observed in Ti2448 alloy, the dislocation loops that were not realized in the past metal materials were observed for the first time under low stress conditions. Uniform nucleation and reversible movement. This new mechanism gives the Ti2448 alloy superior biomechanical properties and more pronounced versatility than other titanium alloys. Ti2448 alloy and its processing and preparation method have been authorized by the national invention patent in 2007.
The Institute of Metal Research of the Chinese Academy of Sciences and the Fourth Military Medical University, China Medical University and other units have conducted continuous cooperative research on the medical application of Ti2448 alloy, and have obtained a large number of detailed and reliable materials, surface biological activity treatment, in vitro cells and animal experiments in vivo. The data; the development of traumatic elastic bone plate, elastic intramedullary nail and spinal elastic fixation system, and carried out biomechanical characterization, fatigue life testing and animal experiments. The above collaborative research results provide an important scientific basis for promoting the medical application of Ti2448 alloy.
At present, the clinical trials of the two types of products have been successfully completed, and Weigao Orthopedic Materials Co., Ltd. has submitted a product registration certificate to the State Food and Drug Administration.
Source: Science Times
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