Coating technology of Chinese medicine pills

Coating technology of Chinese medicine pills

In addition to improving the appearance, taste, and drug stability, the pellet coating is mainly aimed at improving the biopharmaceutical properties of the drug. The coating of the pellets can be carried out in a coating pan or a high-efficiency coating pan, or in an air suspension fluidized bed coating method in a centrifugal granulator, in a fluidized bed, or in a coating liquid. Coating and other methods.
Because the common coating pan coating has the disadvantages of low drying efficiency, large dust pollution, batch difference and long operation time, it is more in the improved coating pan such as the baffle coating pan and the buried tube spray bag. In the clothes pot. The buried spray coating pan is particularly suitable for coating with a water-decomposing body as a coating liquid, which can greatly shorten the coating time.
The air suspension fluid bed coating suspends the pellet in the coating chamber by means of a rapidly rising air flow, so that it is in a non-stop flow state, and sprays the coating solution or suspension into the pellet surface, that is, on the surface of the pellet. And the hot air stream is dried and repeatedly coated until the weight is increased to the desired thickness. The fluidized bed type has a fluidized bed for top spray granulation and coating, a bottom spray coating fluidized bed and a rotary fluidized bed. The key factors affecting the properties of the film during fluidized bed coating are the film temperature and the gun pressure, in addition to the amount of polymer. This method is a very effective slow release coating method, such as fluidized bed cutting. The pellets were prepared by coating.
The immersion coating system spreads the pellets evenly on the sieve mesh, quickly passes through the coating liquid, and is dried together with the sieve mesh, gently flipped, and then quickly passed through the coating liquid. Repeatedly. The specified requirements have been met.

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