Dry pellet quality requirements
1, the main drug content
According to the test method of the finished product of the tablet, the content of the main drug should meet the requirements.
2, water content
The moisture content of dry pellets for traditional Chinese medicine tablets is generally 3%-5%; the moisture content of chemical dry pellets is 1%-3%, except for individual varieties.
3, tightness
It is advisable to dry the granules with a finger to break into a fine powder with a rough feel. Easy to produce granules excellent tableting surface Ma; loose friable particles into a fine powder, is easy to produce capping tabletting.
4, the thickness
The particle size should be selected according to the weight and the chip diameter. Large pieces can be compressed with larger particles or small particles, but small pieces must use smaller particles, otherwise large difference in weight will be caused.
　　 The tableting particles should be composed of different layers of thickness, and the ratio of the coarse and fine particles and the fine powder in each layer is related to the drug properties, the size of the sheet and the mechanical properties. Generally, the 20-30 mesh powder particles in the dry granules are preferably 20% to 40%. If the coarse powder is too much, the weight difference of the pressed tablets is large, and the occurrence of loose pieces, lobes, corner flaking and sticking may be related to excessive fine powder.
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