Release date: 2007-10-22
US research finds prevention strategies that reduce HIV transmission
According to the "Public Science Library? Comprehensive" journal published on September 19, researchers at the University of Pittsburgh School of Medicine found that if people in sub-Saharan African countries insist on taking antiretroviral drugs every day, they will be able to Slowing the spread of AIDS in the region. These findings were based on a mathematical model. The model is primarily used to predict the public health impact of pre-exposure prophylaxis (PrEP) -- an HIV prevention strategy using antiretroviral drugs, which can now be combined with treatment-positive HIV carriers. Use to prevent infection from spreading from the starting location.
These researchers studied three cases of the model: one is optimistic, that is, the assumed use rate can reach 75%, and the time efficiency of pre-exposure chemoprevention can reach 90%; the intermediate situation is that the use rate can reach 50%. The time efficiency of chemoprevention before exposure can reach 60%; the pessimistic situation is only 25% utilization rate, and the time efficiency of pre-exposure chemoprevention is only 30%.
It has been found that under ideal conditions, significant public health benefits can be obtained through pre-exposure chemoprevention techniques. If pre-exposure chemoprevention technology can last for 10 years, it will reduce new HIV infections in sub-Saharan Africa by 74%. Those with intermediate attitudes and pessimistic attitudes believe that pre-exposure chemoprevention can achieve much less results, with intermediate attitudes suggesting that they will only reduce by 24.9%, while pessimists believe that only 3.3%.
Researchers have found an advantage from pre-exposure chemoprevention -- it may play an important role in HIV prevention strategies, potentially having a major impact on public health, and may even be in sub-Saharan Africa within 10 years. The state prevents the occurrence of approximately 3.2 million AIDS cases. Sub-Saharan African countries are the center of the global AIDS epidemic. About 22.4 million adults in the region are infected with AIDS, which accounts for about 63% of the total number of people infected worldwide.
Pre-exposure chemoprevention is based on the assumption that treatment is taken to delay the transmission of HIV before the infection is exposed. Data from animal studies suggest that pre-exposure chemoprevention is a effective means of preventing HIV transmission. ——Midi Medical Network
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