Research finds that nanotechnology can be applied to help diabetic wound healing

Release date: 2015-08-17

People with diabetes often encounter problems with difficult wound healing. Egyptian scientists have developed an antibacterial nanofiber containing silver cellulose acetate, a new medical material used to promote tissue repair. They clarified the details and performance of the new material and published the article in the journal International Journal of Nanoparticles.

Thanaa Ibrahim Shalaby and his colleagues Nivan Mahmoud Fekry, Amel Gaber El Sheredy and Maisa El Sayed Sayed Ahmed Moustafa developed nanofibers made from cellulose acetate at the University of Alexandria, an inexpensive and easy-to-manufacture material. This semi-synthetic polymer can be used on all sides, from film to paint for glasses, and even cigarette filters. It can be re-formed into fibers for use as an absorbent and safe wound medical material. Shalaby and colleagues used a variety of analytical techniques, including scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR), to shape fibers that bind silver nanoparticles.

After shaping the medical materials, the research team successfully tested its antibacterial activity against different strains that may have contracted the wound. They then used the medical material to treat skin wounds and wounds in diabetic mice and then determine whether nanomaterials have an effect on wound healing rate. The team said the medical material absorbs the fluid from the wound, but at the same time protects the wound from infectious agents that are infiltrated into air and moisture. The use of such medical materials also promotes collagen production as the wound heals, which contributes to the relaxation of the normal skin and the growth of texture, which are lacking in the healing of diabetic wounds.

Source: Bio Valley

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