China will launch zui's large-scale prevention of stroke clinical trials

The clinical trial of Zui's large-scale prevention of stroke will be initiated by Peking University People's Hospital as the leader unit and 300 hospitals in China, including cardiology, geriatrics and neurology. The trial will include 15,000 patients with essential hypertension, followed by a multicenter, randomized, double-blind, parallel-controlled, 4-year follow-up, providing a more effective treatment for reducing long-term high incidence of stroke and mortality in China. Combined with therapeutic drugs and provide the basis for the establishment of individualized treatment options.

This clinical trial will directly compare the efficacy of enalapril folic acid tablets (Yiye) and single use of enalapril in reducing the risk of stroke in patients with essential hypertension. Yiye is a class of chemical compound drugs developed by China with independent intellectual property rights. It is a drug specially designed by Chinese scientists for hypertensive patients with high levels of plasma high Hcy (homocysteine) in China. Studies have shown that high blood pressure with high Hcy (homocysteine) accounts for 75% of Chinese high blood pressure. If hypertension is accompanied by an increase in Hcy, the risk of stroke will be 12 times higher than that of healthy people.

The reason why the Chinese Hcy is generally high is multifaceted, and the supplementation of folic acid can significantly reduce it. Chinese scientists draw on the concept of "Junchen Zuozhi" in the motherland medicine, based on long-term large-scale clinical research, according to the characteristics of high incidence of stroke in China and high incidence of Hcy hypertension, the drugs for the treatment of hypertension, enalapril and drugs for lowering Hcy Folic acid is combined to develop a drug that specifically targets high blood pressure with Chinese characteristics.

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