Estrogen Progesterone Powder for Habitual Abortion Dysmenorrhea Amenorrhea

Model NO.: 1
CAS: 57-83-0
MF: C21H30O2
MW: 314.46
Delivery Ways: EMS, Hkems, TNT, DHL, FedEx, UPS etc.
Trademark: HZ
Transport Package: as You Requst
Specification: 99%
Origin: China
HS Code: 2942000000
Model NO.: 1
CAS: 57-83-0
MF: C21H30O2
MW: 314.46
Delivery Ways: EMS, Hkems, TNT, DHL, FedEx, UPS etc.
Trademark: HZ
Transport Package: as You Requst
Specification: 99%
Origin: China
HS Code: 2942000000
Estrogen Progesterone Raw Powder for Habitual Abortion Dysmenorrhea Amenorrhea CAS 57-83-0


Basic information:

Product Name: Progesterone 
Synonyms: PROGESTERONE-WATER SOLUBLE;progestin;PROGESTERONE;PRIMOLUT;17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione;17alpha-Progesterone;3,20-Pregnene-4;4-Pregnen-3,20-dion 
CAS: 57-83-0 
MF: C21H30O2 
MW: 314.46 
CAS:  57-83-0 
MF:  C21H30O2 
MW: 314.46 
EINECS:  200-350-6 

Product Categories: MI;FINISHED MEDICINE;Steroids;ketone;Biochemistry;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Steroid and Hormone;API;ENDOMETRIN;Plant extract;Pharma material;Inhibitors 
Mol File: 57-83-0.mol 


Chemical Properties:

MP  128-132 °C(lit.)
alpha  186 º (c=1, ethanol) 
refractive index  182 ° (C=2, Dioxane) 
storage temp.  Store at RT 
solubility  H2O: 25 mg/mL, may be clear to slightly hazy
form  powder
Water Solubility  <0.1 g/100 mL at 19 ºC 
Merck  7773 
Stability: Stable. Incompatible with strong oxidizing agents. 

Safety Information:

Hazard Codes  Xn,T,F 
Risk Statements  40-45-62-36-20/21/22-11 
Safety Statements  36/37-45-53-16 
WGK Germany  3 
RTECS  TW0175000


Usage And Synthesis:

Formerly biochemical study shows that progesterone modulates action as progestogens, clinical for the treatment of habitual abortion, dysmenorrhea, amenorrhea and other symptoms. One of progesterone's most important functions is as hormone drugs, to promote and maintain the uterine changes in the early stage of pregnancy, used in habitual abortion, irregular menstruation, etc.. In addition, progesterone also behaves as steroid hormone drug as well as progestogens, which is used in treatment of threatened abortion. 

Test method:

In the 40's, only chemical method can be used to monitor the excretion of pregnanediol which is the metabolism of progesterone in the urine of 24h, this could reflect the level of progesterone release. 
Started from the 50's, progesterone levels in plasma could be determined not only by chemical methods, but also by biological methods and gas chromatography.
At the end of the 60's, radionuclides and protein competition were developed to determine progesterone.
In the 70's, the radiation immune assay and the radiation receptor method have appeared, which greatly improved the sensitivity and accuracy of the assay. When determination of progesterone in blood has been widely used, the determination of urinary progesterone has lost its importance. Normal value of follicular phase in urine was 1mg/24h, and in the corpus phase was 2-8mg/24h. Changes of progesterone levels in women of childbearing age can reflect the different stages of the menstrual cycle. For pregnant women, blood progesterone continued rising, which is not coincidence with the normal cycle. For the person of congenital 17α-hydroxylase deficiency syndrome, there is abnormal ratio of progesterone to 17α-Hydroxy progesterone, that is progesterone ascending while 17α-Hydroxy progesterone decreasing.

Preparation Products And Raw materials:

Raw materials Cyclohexanone-->16-Dehydropregnenolone acetate-->Aluminium isopropoxide-->Pregnenolone 
Preparation Products Deoxycorticosterone acetate -->-17-acetate-->17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione 21-acetate-->9-Bromo-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-21-acetate-->9beta,11beta-epoxy-17,21-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate-->16,17-Epoxypregna-5,9(11)-diene-3,20-dione cyclic bis(1,2-ethanediyl acetal)-->17-Hydroxy-16-methylpregna-5,9(11)-diene-3,20-dione 3,20-diethyleneketal-->16-Dehydroprogesterone 

  Estrogen Progesterone Raw Powder for Habitual Abortion Dysmenorrhea Amenorrhea CAS 57-83-0


Basic information:

Product Name: Progesterone 
Synonyms: PROGESTERONE-WATER SOLUBLE;progestin;PROGESTERONE;PRIMOLUT;17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione;17alpha-Progesterone;3,20-Pregnene-4;4-Pregnen-3,20-dion 
CAS: 57-83-0 
MF: C21H30O2 
MW: 314.46 
CAS:  57-83-0 
MF:  C21H30O2 
MW: 314.46 
EINECS:  200-350-6 

Product Categories: MI;FINISHED MEDICINE;Steroids;ketone;Biochemistry;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Steroid and Hormone;API;ENDOMETRIN;Plant extract;Pharma material;Inhibitors 
Mol File: 57-83-0.mol 


Chemical Properties:

MP  128-132 °C(lit.)
alpha  186 º (c=1, ethanol) 
refractive index  182 ° (C=2, Dioxane) 
storage temp.  Store at RT 
solubility  H2O: 25 mg/mL, may be clear to slightly hazy
form  powder
Water Solubility  <0.1 g/100 mL at 19 ºC 
Merck  7773 
Stability: Stable. Incompatible with strong oxidizing agents. 

Safety Information:

Hazard Codes  Xn,T,F 
Risk Statements  40-45-62-36-20/21/22-11 
Safety Statements  36/37-45-53-16 
WGK Germany  3 
RTECS  TW0175000


Usage And Synthesis:

Formerly biochemical study shows that progesterone modulates action as progestogens, clinical for the treatment of habitual abortion, dysmenorrhea, amenorrhea and other symptoms. One of progesterone's most important functions is as hormone drugs, to promote and maintain the uterine changes in the early stage of pregnancy, used in habitual abortion, irregular menstruation, etc.. In addition, progesterone also behaves as steroid hormone drug as well as progestogens, which is used in treatment of threatened abortion. 

Test method:

In the 40's, only chemical method can be used to monitor the excretion of pregnanediol which is the metabolism of progesterone in the urine of 24h, this could reflect the level of progesterone release. 
Started from the 50's, progesterone levels in plasma could be determined not only by chemical methods, but also by biological methods and gas chromatography.
At the end of the 60's, radionuclides and protein competition were developed to determine progesterone.
In the 70's, the radiation immune assay and the radiation receptor method have appeared, which greatly improved the sensitivity and accuracy of the assay. When determination of progesterone in blood has been widely used, the determination of urinary progesterone has lost its importance. Normal value of follicular phase in urine was 1mg/24h, and in the corpus phase was 2-8mg/24h. Changes of progesterone levels in women of childbearing age can reflect the different stages of the menstrual cycle. For pregnant women, blood progesterone continued rising, which is not coincidence with the normal cycle. For the person of congenital 17α-hydroxylase deficiency syndrome, there is abnormal ratio of progesterone to 17α-Hydroxy progesterone, that is progesterone ascending while 17α-Hydroxy progesterone decreasing.

Preparation Products And Raw materials:

Raw materials Cyclohexanone-->16-Dehydropregnenolone acetate-->Aluminium isopropoxide-->Pregnenolone 
Preparation Products Deoxycorticosterone acetate -->-17-acetate-->17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione 21-acetate-->9-Bromo-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-21-acetate-->9beta,11beta-epoxy-17,21-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate-->16,17-Epoxypregna-5,9(11)-diene-3,20-dione cyclic bis(1,2-ethanediyl acetal)-->17-Hydroxy-16-methylpregna-5,9(11)-diene-3,20-dione 3,20-diethyleneketal-->16-Dehydroprogesterone 

 

Diagnostic & Rehabilitation Ancillary Products

Walking Aid,Aluminum Alloy Walking Aid,Aluminum Walking Aid

Henso Medical Co., Ltd. , http://www.hzurology.com